One of the grand scientific challenges of the 21st century is to be able to control chemical reaction pathways for specific results (the modern alchemy). Before this can happen, experimental tools must be developed to enable scientists to follow the change of the molecules at their own natural timescale-typically a few femtoseconds, and the positions of the constituent atoms-at sub-Angstrom resolutions. In this talk I will discuss three different methods based on technology that is nearly or already available where one can film the movement of atoms in a dynamically evolving molecule. The methods are all based on electron diffraction, where electrons are either generated by X-ray free-electron lasers (XFEL), or by rescattering electrons generated by mid-infrared lasers.