In this talk, efforts based on nanoplasmonic engineering of near-fields for biosensing and imaging will be described. The creation of localized near-fields has been investigated in many past works because the approach allows the potential to improve detection sensitivity and to enhance resolving power in imaging applications. First application to be discussed is for label-free biosensing in which biomolecular interaction can be measured in real time on a quantitative basis. Another application of nanoplasmonics is for improvement of resolving power that has drawn tremendous attention for imaging molecular processes typically impossible to observe under diffraction limit. While emerging approaches have been extremely successful to produce super-resolved images, we explore alternative approaches based on nanoplasmonics by which achievable resolution may be customized to fit the specific imaging needs and at the same time a conventional optical system may be used. Feasibility studies performed on visualizing internalization of virus particles, sliding microtubules and bacterial motility on random and periodic nanopatterns will be presented.

报告人简介: Dr. Donghyun Kim received the B.S. and M.S. in electronics engineering from Seoul National University, Seoul, Korea, in 1993 and 1995, and Ph.D. in electrical engineering from Massachusetts Institute of Technology (MIT) in 2001. He was with Corning Inc., Corning, NY, as a Sr. Research Scientist and with Cornell University, Ithaca, NY, as a Postdoctoral Associate. Since 2004, he has been with the School of Electrical and Electronic Engineering, Yonsei University. Dr. Kim leads an optics group with research interests in biomedical applications of optics and optoelectronics focused on evanescent wave-based techniques such as highly sensitive surface plasmon resonance biosensors and plasmon-enhanced live-cell imaging. Since 2011, he has been leading the Nanoplasmonic Imaging National Research Laboratory funded by the National Research Foundation of Korea.