Light, in many ways, is an ideal form of electromagnetic waves to probe biological tissues as light can interact with almost all kind of molecules. Biomedical optical imaging, however, encounters an inevitable trade-off between resolution and penetration depth due to the strong scattering of light in tissue. Here we summarize our endeavors in the past years of using the synergy of light and sound to achieve high-resolution optical focusing, imaging, and stimulation within or through thick scattering media based on optical wavefront shaping and deep learning. Limitations, potential applications, and further direction are also discussed.

报告人简介：Dr. Puxiang Lai received his Bachelor from Tsinghua University in 2002, Master from Chinese Academy of Sciences in 2005, and PhD from Boston University in 2011. After that, he joined Dr Lihong Wang’s lab in Washington University in St. Louis as a Postdoctoral Research Associate. In September 2015, he joined Department of Biomedical Engineering at the Hong Kong Polytechnic University. Dr. Lai’s research focuses on the synergy of light and sound as well as its applications in biomedicine. His research has fueled more than 40 top journal publications, such as Nature Photonics and Nature Communications.